Splenomegaly in Kawasaki Disease: A Pitfall in Diagnosis.

Among the 365 children diagnosed as having Kawasaki disease (KD), only 5 children (1.4%) presented with splenomegaly: 2 complicated by macrophage activation syndrome and 3 ultimately received a diagnosis of alternative systemic illness. Splenomegaly is atypical in KD and a potential marker of an underling complication, namely macrophage activation syndrome, or diagnosis other than KD.

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TitleSplenomegaly in Kawasaki Disease: A Pitfall in Diagnosis.
Date2023-06-01
Issue nameThe Journal of pediatrics
Issue numberv257:113359
DOI10.1016/j.jpeds.2023.02.006
PubMed36813130
AuthorsMiselli F, Mastrolia MV, Simonini G, Trapani S & Calabri GB
Keywordsdifferential diagnosis, macrophage activation syndrome
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